Hsiu-Mei Chang1, Ben-Ran Fu This email address is being protected from spambots. You need JavaScript enabled to view it.2, Hao-Wei Yu3, Fu-Tsai Chung1,4,5,6, Chen-June Seak6,7, Ying-Chun Chen3, Shih-Cheng Hu This email address is being protected from spambots. You need JavaScript enabled to view it.3 

1 Department of Respiratory Therapy, New Taipei Municipal Tucheng Hospital, Managed by Chang Gung Medical Foundation, New Taipei City, Taiwan
2 Department of Mechanical Engineering, National Yang Ming Chiao Tung University, Hsinchu, Taiwan
3 Department of Energy and Refrigerating Air-conditioning Engineering, National Taipei University of Technology, Taipei, Taiwan
4 Department of Thoracic Medicine, New Taipei Municipal Tucheng Hospital, Managed by Chang Gung Medical Foundation, New Taipei City, Taiwan
5 Department of Thoracic Medicine, Chang Gung Memorial Hospital at Linkou, Taoyuan City, Taiwan
6 College of Medicine, Chang Gung University, Taoyuan City, Taiwan
7 Department of Emergency Medicine, New Taipei Municipal Tucheng Hospital, Managed by Chang Gung Medical Foundation, New Taipei City, Taiwan


Received: November 20, 2023
Revised: April 20, 2024
Accepted: April 28, 2024

 Copyright The Author(s). This is an open access article distributed under the terms of the Creative Commons Attribution License (CC BY 4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are cited.


Download Citation: ||https://doi.org/10.4209/aaqr.230285  

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Cite this article:

Chang, H.M., Fu, B.R., Yu, H.W., Chung, F.T., Seak, C.J., Chen, Y.C., Hu, S.C. (2024). Effectiveness of a Protective Barrier for Aerosol Transmission Control during Oxygen Therapy with Different Devices. Aerosol Air Qual. Res. 24, 230285. https://doi.org/10.4209/aaqr.230285


HIGHLIGHTS

  • The effect of the protective barrier on the aerosol leakage levels was studied.
  • Patient simulators were tested for aerosol dispersion tests.
  • The aerosol concentration was increased after using nebulized drug delivery.
  • Using air extraction and protective barrier, the improvement rate was the highest.
 

ABSTRACT


This study investigated the effects of an air extraction system or a protective barrier on aerosol leakage levels using experiments conducted inside the hospital negative-pressure isolation rooms. Patient simulators were tested with five different oxygen supply devices for aerosol dispersion tests: an endotracheal tube (ET), a non-invasive ventilation (NIV) mask, high-flow nasal cannula (HFNC), a simple mask, and a non-rebreather (NR) mask. The effects of nebulized drug delivery on aerosol concentration were also investigated. The results showed that aerosol concentration was generally higher after using nebulized drug delivery than without it. For cases with HFNC and simple and NR masks, the aerosol concentrations were relatively higher, usually one to two orders of magnitude greater than those in cases with ET and NIV masks. Experiments using solely protective barrier (Case C) showed higher improvements in aerosol leakage than those using only the air extraction system (Case B); however, aerosol accumulation within the protective barrier remains an issue. In cases (Case D) using both the air extraction system and a protective barrier, the improvements were the highest, with some values even exceeding 99%; additionally, the aerosol concentration within the protective barrier was reduced. This could potentially reduce the risk of infection for healthcare workers during clinical applications. In summary, the ability to prevent aerosol leakage is ranked as follows: Case D > Case C > Case B.


Keywords: Protective barrier, Aerosol transmission, Negative-pressure environment




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