Yizhuo Zhao1,2, Suo Zhang3†, Liqiong Guo4,5, Meng Xiao1,2, Zhuo Han1,2, Yuewei Yang1,2, Bo Wang This email address is being protected from spambots. You need JavaScript enabled to view it.1,2, Penghui Li  1,2

1 School of Environmental Science and Safety Engineering, Tianjin University of Technology, Tianjin 300384, China
2 Tianjin Key Laboratory of Hazardous Waste Safety Disposal and Recycling Technology, Tianjin 300384, China
3 Shanghai Municipal Engineering Design Institute (Group) Co., Ltd., Tianjin Branchi, Tianjin 300220, China
4 Wenzhou Safety (Emergency) Institute, Tianjin University, Wenzhou 325000, China
5 Institute of Disaster and Emergency Medicine, Tianjin University, Tianjin 300072, China

These authors contributed equally to this work

Received: August 20, 2023
Revised: October 16, 2023
Accepted: October 18, 2023

 Copyright The Author(s). This is an open access article distributed under the terms of the Creative Commons Attribution License (CC BY 4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are cited.

Download Citation: ||https://doi.org/10.4209/aaqr.230197  

Cite this article:

Zhao, Y., Zhang, S., Guo, L., Xiao, M., Han, Z., Yang, Y., Wang, B., Li, P. (2023). Association between Air Pollutants and the Risk of Sleep Disorders: A Systematic Review and Meta-analysis. Aerosol Air Qual. Res. 24, 230197. https://doi.org/10.4209/aaqr.230197


  • This is the first meta-analysis of air pollution and sleep disorders.
  • Three atmospheric pollutants (PM2.5, PM10, NO2) are associated with sleep disorders.
  • Related literature in 23 years were identified.
  • Subgroup analyses were conducted by subgroups divided into 7 categories.


Background: Sleep disorders have become prevalent, but the association between air pollutants and the risk of sleep disorders remains unclear. In this study, a meta-analysis was carried out to examine this relationship.

Methods: A systematic review and meta-analysis for publications from January 1, 2000 to February 1, 2023 was conducted to clarify the association between air pollutants and the risk of sleep disorders.

Results: We identified 18027 articles from ScienceDirect, Web of Science, PubMed, and Embase, and 10 met our inclusion criteria. The results suggested that there were significant positive associations between PM2.5, PM10, NO2 exposure and sleep disorders (for each 10 µg m3 increment of PM2.5, PM10, and NO2, OR: 2.50, 95% CI: 1.87–3.32; OR: 1.15, 95% CI: 1.06–1.24; OR: 1.36; 95% CI: 1.17–1.59, respectively).

Conclusions: Exposure to PM2.5, PM10, and NO2 can lead to an increased risk of sleep disorders. Further studies with other pollutants are needed to clarify the association between air pollutants and sleep disorders.

Keywords: Air pollutants, Sleep disorders, Insomnia, Systematic review, Meta‐analysis

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