Bibo Yuan1, Citlalli Osorio-Yáñez2, Junkai Fang3, Lei Zhao4,5,6, Ander Wilson7, Marco Sanchez-Guerra8, Hongbin Liu3, Peng-Hui Li This email address is being protected from spambots. You need JavaScript enabled to view it.9, Liqiong Guo This email address is being protected from spambots. You need JavaScript enabled to view it.4,5,6 

1 Department of Gynecology and Obstetrics, Tianjin Medical University General Hospital, Tianjin 300052, China
2 Instituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de México, México DF 04510, Mexico
3 Tianjin Institute of Medical & Pharmaceutical Sciences, Tianjin 300070, China
4 Institute of Disaster Medicine, Tianjin University, Tianjin 300072, China
5 Tianjin Key Laboratory of Disaster Medicine Technology, Tianjin 300072, China
6 Wenzhou Safety (Emergency) Institute, Tianjin University, Wenzhou 325000, China
7 Department of Statistics, Colorado State University, Fort Collins, Colorado 80523, USA
8 Department of Developmental Neurobiology, National Institute of Perinatology, Mexico City 04510, Mexico
9 School of Environmental Science and Safety Engineering, Tianjin University of Technology, Tianjin 300384, China


Received: April 13, 2021
Revised: June 2, 2021
Accepted: June 4, 2021

 Copyright The Author(s). This is an open access article distributed under the terms of the Creative Commons Attribution License (CC BY 4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are cited.


Download Citation: ||https://doi.org/10.4209/aaqr.210085  


Cite this article:

Yuan, B., Osorio-Yáñez, C., Fang, J., Zhao, L., Wilson, A., Sanchez-Guerra, M., Liu, H., Li, P.H., Guo, L. (2021). Effect of Radiation, Organic Solvents and Vibration Occupational Exposure on the Thyroid Disease. Aerosol Air Qual. Res. https://doi.org/10.4209/aaqr.210085


HIGHLIGHTS

  • Thyroid disease was significantly associated with occupational exposure.
  • The prevalence of thyroid disease was higher in women compared to men.
  • Higher TSH levels were found in women with occupational vibration exposure.
 

ABSTRACT


Thyroid disease is one of the leading endocrine disorders. Occupational exposure to radiation and organic solvents are known to be risk factors, but much less is known about the effect of vibration exposure on thyroid disease risk. The aim of this study was to examine associations between occupational exposure to radiation, organic solvents and vibration in relation to thyroid disease risk and thyroid stimulating hormone (TSH) levels. We utilized Project ELEFANT, comprising 124,286 participants from Tianjin, China. Medical records including thyroid disease history were collected, and TSH levels were measured in women by automated immunometric assay. In logistic models adjusted for confounders, exposure to radiation (odds ratio, OR: 1.73; 95% CI: 1.1-2.7), organic solvents (OR: 2.0; 95% CI: 1.3-2.9) and vibration (OR: 4.4; 95% CI: 2.0-8.75) were significantly associated with increased risk of thyroid disease. TSH concentrations in female participants (median: 1.95 and 95% CI: 2.45-2.77) were associated only with vibration exposure (ß: 2.80; 95% CI: 1.07-4.54). Our data showed for the first time that vibration exposure is associated with increased risk of thyroid disease and raised TSH hormone levels. If confirmed in other cohorts, thyroid examinations should be conducted in workers exposed to vibration in the workplace.


Keywords: Vibration, Organic solvents, Radiation, Thyroid disease, Thyroid stimulating hormone




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