Chenxi Zhang This email address is being protected from spambots. You need JavaScript enabled to view it.1,2, Xuesong Cao2, Xiaomin Sun2, Hengjun Peng This email address is being protected from spambots. You need JavaScript enabled to view it.3 

1 College of Biological and Environmental Engineering, Binzhou University, Binzhou 256600, China
2 Environment Research Institute, Shandong University, Qingdao 266200, China
3 Logistics support department, Shandong University, Jinan 250100, China

Received: November 19, 2020
Revised: February 18, 2021
Accepted: March 2, 2021

 Copyright The Author(s). This is an open access article distributed under the terms of the Creative Commons Attribution License (CC BY 4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are cited.

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Zhang, C., Cao, X., Sun, X., Peng, H. (2021). Study on the Formation of Secondary Organic Aerosol by Ozonolysis of Citral in the Atmosphere. Aerosol Air Qual. Res. 21, 200637.


  • The k of H2O and SO2 with CIs are close to the reported experimental value.
  • CIs can react with SO2 to generate a carbonyl compound and SO3.
  • Ozonolysis of Citral can produce low volatile organic compounds, which can form SOA.


A major research area in atmospheric chemistry focuses on the formation of secondary organic aerosol (SOA), which contains a large variety of low-volatility organic compounds when generated by the ozonolysis of monoterpenes. Thus, we apply quantum chemistry and kinetic calculations to investigate the ozonolysis of citral, which begins with the formation of primary ozonides (POZs) that decompose into Criegee intermediates (CIs). Although CIs have been previously implicated in tropospheric oxidation, the majority are simple compounds for their class, such as CH2OO· or CH3CHOO·. This study, however, reports on the generation and reaction kinetics of larger CIs, which have been shown to oxidize NO and SO2 into NO2 and SO3, respectively, leading to the production of nitric acid and sulfuric acid. Furthermore, the reactions between these CIs, and H2O and SO2 may serve as the dominant mechanism for removing the former from the troposphere, thereby determining the atmospheric CI concentrations. The low-volatility organic compounds potentially arising from the ozonolysis of citral, including aldehydes (–C(=O)H), ketones (–C(=O)–), alcohols (–OH), and hydroperoxides (–OOH), can form SOA through the nucleation, condensation, and/or partitioning of the condensed and gaseous phases.

Keywords: Secondary organic aerosol, Citral, Ozonolysis, Criegee intermediates


Atmospheric aerosols significantly affect the earth’s radiation balance by absorbing and scattering solar radiation, leading to a decrease in atmospheric visibility and contributing to climate change. Moreover, due to the small particle size and large surface area of atmospheric aerosols, they provide a reaction bed for various atmospheric chemical processes and have a direct effect on human health (Oberdorster et al., 2005; Pope and Dockery, 2006). Atmospheric aerosols are mainly classified as either primary aerosols which are directly discharged into the atmosphere by an exhaust source, or secondary aerosols formed in the atmosphere from chemical reaction with gaseous components (Atkinson and Arey, 2003; Hallquist et al., 2009). Secondary organic aerosols (SOAs) are mainly formed from the oxidation processes of volatile organic compounds (VOCs) and account for a significant fraction of ambient tropospheric aerosols (Jimenez et al., 2009).

About 90% of the total global VOCs emissions that lead to SOAs formation come from biological sources, which including isoprene (C5H8), monoterpenes (C10H16), and sesquiterpenes (C15H24) (Guenther et al., 1995; Goldstein and Galbally, 2007; Friedman and Farmer, 2018; Stangl et al., 2019). Monoterpenes have been found to be the largest contributors to organic aerosol during the summer in the southeastern United States, with mean global emissions estimated to be approximately 107.5 TgC per year (Messina et al., 2016; Zhang et al., 2018; Nagori et al., 2019). As monoterpenes are unsaturated, they rapidly react with O3, OH and NO3 radicals, with estimated reaction rates for OH and NO3 radicals with most monoterpenes being larger than 10–11 cm3 molecules–1 s–1 and in the range of 10–19–10–14 cm3 molecules–1 s–1 for O3 with monoterpenes (Atkinson, 1997; Calogirou et al., 1999; Martínez et al., 1999; Orlando et al., 2000; Oliveira and Bauerfeldt, 2012). Using the 12-h daytime average OH radical concentration of 2 × 106 molecules cm3, 12-h nighttime average NO3 radical concentration of 2.5 × 108 molecules cm3 and 24-h average O3 concentration of 7 × 1011 molecules cm–3, the fast monoterpene ozonolysis reaction can compete with the OH reaction during the day and the NO3 reaction at night. Therefore, ozonolysis serves as an important monoterpene loss pathway (Orlando et al., 2000; Atkinson and Arey, 2003; Qin et al., 2018). In addition, a large variety of low-volatility organic compounds, including carbonyl compounds (aldehydes and ketones), hydroxyl compounds and organic acids, have been identified in SOAs generated from the ozonolysis of monoterpenes, such as α-pinene, β-pinene, α-phellandrene, limonene, and sabinene (Jacksonet et al., 2016; Sato et al., 2016; Scorch et al., 2017). Therefore, SOAs formation by the oxidation of monoterpenes is mainly dominated by the ozonolysis reaction.

Monoterpenes generally contain 1–3 unsaturated >C=C< double bonds and are highly reactive. The proposed reaction mechanism for monoterpene ozonolysis starts with O3 addition to C=C double bonds, which lead to the formation of primary ozonide (POZ). The formed POZ will then rapidly decompose to form Criegee intermediates (CIs). Chemically activated CIs may undergo unimolecular decomposition or isomerization, or bimolecular reactions with H2O, NO and SO2 (Kleindienst et al., 2006; Jaoui et al., 2008; Lin et al., 2014; Jackson et al., 2017; Almatarneh et al., 2019), with many previous studies reporting the importance of bimolecular reactions for SOA formation.

Neeb et al. (1997) found that hydroxymethyl hydroperoxide (HMHP) was the sole product of the reaction between CH2OO and water H2O. HMHP can then be rapidly decomposed into low-volatility organic compounds such as methacrolein and methyl vinyl ketone (Sauer et al., 1999). Presto et al. (2005) reported SOA yields from the ozonolysis of α-pinene in the presence of NOx, suggesting that CIs can react with NO, typically resulting in carbonyl and organic nitrate functionality. Mauldin et al. (2012) found that the oxidation of SO2 to H2SO4 by CIs leads to an increase in the production of sulfate aerosols in boreal forests. Sipilä et al. (2014) also reported that the reaction between SO2 and CIs formed from monoterpene ozonolysis is an important source of atmospheric sulfate and SOAs. In addition, Ye et al. (2018) studied α-pinene and limonene ozonolysis in the presence of SO2, finding that the reaction of SO2 with CIs was responsible for altering SOAs yields. Although these experimental studies indicated that bimolecular CIs reactions were related to SOAs formation, the chemical processes behind these interactions are not yet fully understood. Moreover, most theoretical studies have focused on small CIs, especially the simple carbonyl oxide CH2OO (Aplincourt and Ruiz-López, 2000; Vereecken et al., 2012; Nguyen et al., 2016). Therefore, it is necessary to study the specific mechanism of SOAs formation from large CIs formed from monoterpene ozonolysis.

As a natural acyclic monoterpene, citral is found in a wide variety of plants, such as Indian lemon grass species and Litsea cubeba, and can be used as a key ingredient for various chemical products (Rauber et al., 2005; Gil et al., 2007; Saddiq and Khayyat, 2010). Citral (3,7-dimethyl-2,6-octadienal) is a mixture of two isomeric acyclic monoterpene aldehydes, neral and geranial (Fig. 1), caused by cis-trans isomerism at the C=C bond near the aldehyde group. In this article, neral was used to theoretically explore the gas-phase ozonolysis of citral in the presence of H2O, NO and SO2, providing novel insights on the formation mechanisms of SOAs during monoterpenes ozonolysis and further deepening our understanding of the atmospheric SOAs.

Fig. 1. The structure of neral and geranial.
Fig. 1. The structure of neral and geranial.


All geometric optimizations were performed using the Gaussian 09 program (Frisch et al., 2009). And in each elementary reaction, the geometric parameters of reactants, pre-reactive complex (PRC), intermediates (IMs), transition states (TSs) and products, were optimized using the M06-2X functional with the 6-31+G(d,p) basis set. Zheng et al. (2009) calculated the barrier heights of DBH24/08 database using 348 model chemistries, including heavy-atom transfer (HATBH6), nucleophilic substitution (NSBH6), unimolecular and association (UABH6), and hydrogen-transfer (HTBH6) reactions. The selected functional M06-2X/6-31+G(d,p) was proven to be reliable and appropriate for the configuration optimization and thermodynamic calculation of ozonolysis (Sun et al., 2018; Wang et al., 2019). At the same level of theory, frequency calculations were performed to obtain zero-point energy corrections. The transition states were identified by only one imaginary frequency. More accurate single energies could be obtained using a larger basis set of 6-311++G(3df,3pd).

Using the KiSThelP program (Truhlar et al., 1996; Canneaux et al., 2014), rate constants were calculated using transition-state theory (TST) with Wigner tunneling correction at a pressure of 1.0 bar and 298 K. A scaling factor of 0.967 was applied to the frequency calculated at the M06-2X/6-31+G(d,p) level (Alecu et al., 2010).

When the reaction involved pre-reactive complexes, the reaction rate constants were calculated using the formula described in Eq. (1) (Shiroudi and Deleuze, 2014), as follows:


where Keq represents the equilibrium constant for the first reaction step, R1…R2 means the pre-reactive complexes. The thermodynamic expression of the equilibrium constant for gas-phase reactions is employed in KiSThelP, as described in Eq. (2) as follows:


where ΔG0(T) is the associated standard reaction Gibbs energy at temperature T and R is the ideal gas constant. Furthermore, the unimolecular reaction rate constant (k1) employed in KiSThelP is the thermodynamic equivalent of Eq. (3):


where σ is the reaction path degeneracy; kb is Boltzmann’s constant; T is the temperature; h is Planck’s constant; R is the ideal gas constant and P0 = 1 bar, with the RT/P0 unit being the inverse of a concentration; Δn is 1 or 0 for gas-phase bimolecular or unimolecular reactions; and ΔG0,≠(T) represents the standard Gibbs free energy of activation for the reaction.

The overall rate constant can be calculated according to Eq. (4) as follows:



3.1 The Formation and Decomposition of Primary Ozonides

Atomic labels are marked in the structure of citral in Fig. 1Fig. 2 depicts the detailed reaction mechanism for the formation and decomposition of POZs, in which the potential barriers (ΔEb) and reaction heats (ΔEr) are also given. Evidently, the reaction of citral with O3 follows the Criegee mechanism, consisting of a three-step reaction: (1) formation of PRCs, (2) electrophilic addition forming 5-member-ring primary ozonides (POZs), and (3) decomposition of POZs.

Fig. 2. The mechanisms for the formation and decomposition of primary ozonides at the M06-2X/6-311++G(3df,3pd)//M06-2X/6-31+G(d,p) level of theory (kcal mol−1).Fig. 2. The mechanisms for the formation and decomposition of primary ozonides at the M06-2X/6-311++G(3df,3pd)//M06-2X/6-31+G(d,p) level of theory (kcal mol−1).

The ozonolysis of citral initiates with the addition of two terminal O atoms of O3 to C2=C3 and C7=C8, obtaining two PRCs (PRC1 and PRC2), with the two reactions release 6.03 kcal mol–1 and 4.91 kcal mol–1 of heat, respectively. Then the POZs (IM1 and IM2) are formed through TS1 and TS2. The barrier heights of these two parallel processes are 4.20 kcal mol–1 and 6.39 kcal mol–1, and the exothermic heat is 65.86 kcal mol–1 and 56.11 kcal mol–1, respectively. Therefore, the reaction of O3 with citral occurs easily under conventional atmospheric conditions.

Energized POZs have a 5-membered ring, which decomposes promptly to form carbonyl compounds [IM3, (CH3)2CO, IM5 and OHCCHO] and the corresponding CIs [IM4, (CH3)2COO·, IM6 and OHCCHOO·] through the cleavage of the C–C bond and one of the O–O bonds.

Table 1 lists the calculated rate coefficients k of O3 with citral at 298 K. The predicted rate coefficient of O3 with citral at 298 K was 6.97 × 10–17 cm3 molecules–1 s–1, falling within the previously reported range of 10–19–10–14 cm3 molecules–1 s–1. Additions to C2=C3 bond account for more than 99% of the branching ratio and thus, further analysis focuses on the fate after addition to C2=C3 bond only.

Table 1. Calculated rate constants for the ozonolysis of citral and Criegee intermediate reactions. 

3.2 Criegee Intermediate Reactions

The addition of O3 to the C2=C3 bond will be decomposed into two CIs, (CH3)2COO· and IM4. The reactions of (CH3)2COO· have been widely investigated in recent studies (Vereecken et al., 2012; Chhantyal-Pun et al., 2017; Deng et al., 2018). In the atmosphere, the stabilized (CH3)2COO· can undergo unimolecular isomerization reaction to form CH2=C(CH3)OOH, and can also react with SO2, NO2, and H2O (Deng et al., 2018). The present study focused on the fate of IM4, which may also undergo unimolecular reactions, or bimolecular reactions with water vapor and other trace gases, e.g., H2O, SO2 and NO2Fig. 3 shows the profile of the potential energy surface for the reaction of IM4. The single molecular degradation of large CIs includes the hydrogen-shift reaction, the bicyclic ring closure reactions and ring cyclization to form dioxirane (DO; Long et al., 2019). Instead of intramolecular hydrogen migration and the bicyclic ring closure reactions, IM4 can undergo ring cyclization to form DO via an exothermic process and with a reaction barrier of about 22.20 kcal mol–1. The rate coefficients at 298 K were estimated as 1.59 × 10–3 s–1.

Fig. 3. The profile of the potential energy surface for the reaction of Criegee intermediates at the M06-2X/6-311++G(3df,3pd)//M06-2X/6-31+G(d,p) level of theory (kcal mol−1).Fig. 3. The profile of the potential energy surface for the reaction of Criegee intermediates at the M06-2X/6-311++G(3df,3pd)//M06-2X/6-31+G(d,p) level of theory (kcal mol−1).

3.2.1 Reaction with H2O

In atmospheric chemistry, one of the most important reactions is considered to be the reaction with H2O because of its high abundance. Previous theoretical and experimental studies have shown that the reaction between CIs and H2O occurs via three main reaction channels (Qi and Chao, 2007; Wang et al., 2019). The pathway to produce organic peroxides is likely to be thermodynamically and kinetically advantageous compared with the other two pathways. In this channel, the H-O bond in H2O is broken to generate OH group and H atom. The obtained OH group is attached to the C atom, while the H atom is simultaneously combined with COO· to form hydroxyalkyl hydroperoxides (HAHP). This process crosses a small potential barrier of 3.31 kcal mol–1 and is highly exothermic, generating 43.43 kcal mol–1 of energy.

For reaction with water, the rate coefficient at 298 K was estimated as 5.07 × 1016 cm3 molecules–1 s–1 based on the TST, which is similar to the rate coefficient of 2.46 × 1016 cm3 molecules–1 s–1 for CH3CHOO (Wang and Wang, 2017). Theoretical studies have also shown that the reaction between (CH3)2COO and water monomer is slow, and the rate coefficients at 298 K is 2.4 × 1017 cm3 molecules–1 s–1 (Anglada and Sole, 2016).

When the relative humidity (RH) is 50%, the concentration of water vapor is about 3.8 × 1017 molecules cm3. Then the effective bimolecular rate is 193 s–1, which is much higher than the unimolecular rate of 1.59 × 103 s–1.

3.2.2 Reaction with NO

In the presence of NOx, CIs can react with NO radicals, resulting in the formation of carbonyl and organic nitrate functionality. Two reaction pathways were established for the reaction between CIs and NO. The first is the formation of a 5-membered ring adduct with a nitrogen-centered radical, with a reaction barrier calculated at 9.12 kcal mol–1; then step by step the C-O bond and O-O bond will break, resulting in the formation of carbonyl compounds and NO2. The other pathway involves NO extraction of the terminal oxygen of CI, which directly generates carbonyl compounds and NO2. The reaction barrier for this pathway is slightly higher than that of cycloaddition, at 13.58 kcal mol–1.

Overall, it may be concluded that the reaction between CI and NO yields a carbonyl compound and NO2, proceeding mostly through the formation of a cyclic intermediate. The NO reaction may act as a route for oxidizing NO to NO2 in the atmosphere, affecting NO/NO2 conversion rates. The associated NO-NO2 cycling is particularly important for the production of tropospheric O3 (Murray et al., 2013; Newsome and Evans, 2017; Ridley et al., 2017). O3 is produced by the photolysis of NO2 during the day, and reacts irreversibly with NO to form NO2 at night. But the presence of CIs may compete with O3 and reduce the reaction between NO and O3 at night, leading to the accumulation of O3.

The overall rate coefficient of IM4 with NO was estimated as 6.85 × 10–21 cm3 molecules–1 s–1 at 298 K, which is 2–3 orders of magnitude lower than the estimated rate coefficient (Vereecken et al., 2012). The concentrations of NO in forests, rural areas and cities are 3.3–4.8 × 108, 1.1 × 1010 and 9 × 1010 molecules cm–3, respectively. Thus, the effective bimolecular rate of IM4 with NO is 2.26 × 10–12–6.17 × 10–10 s–1.

3.2.3 Reaction with SO2

In the atmosphere, the Criegee intermediate IM4 can also undergo bimolecular reactions with SO2, which begins with the formation of a pre-reactive complex (PRC-SO2). This process releases 13.57 kcal mol–1 of energy. Then the 5-membered ring adduct IM1-SO2 is obtained via TS1-SO2, with this process being constrained by a reaction barrier height of 1.02 kcal mol–1 and being exothermic by 23.67 kcal mol–1. Finally, the 5-membered ring intermediate breaks the O-O and C-O bonds to form a carbonyl compound (IM3) and SO3. SO3 condenses with water to form fine sulfate aerosol particles in the atmosphere, which not only affects global climate change, but also

harms human health (Sarwar et al., 2013). This pathway can also account for non-OH sources in the atmosphere leading to increased sulfate aerosol production in coastal (Berresheim et al., 2014) and boreal forest environments (Mauldin et al., 2012).

The overall rate coefficient k of SO2 with IM4 is 3.19 × 10–10 cm3 molecules–1 s–1 at ambient temperature and 760 Torr, which is close to the previously reported experimental values of 2.4–6.7 × 10–11 cm3 molecules–1 s–1 for CH3CHOO (Taatjes et al., 2013), 1.3 × 10–11 cm3 molecules–1 s–1 for (CH3)2COO (Huang et al., 2015), and (4.2 ± 0.6) × 10–11 cm3 molecules–1 s–1 for methyl vinyl ketone oxide (Caravan et al., 2020), as well as the theoretical values of (3.68 ± 0.02) × 10–11 cm3 molecules–1 s–1 for CH2OO (Kuwata et al., 2015) and 5.27–6.54 × 10–10 cm3 molecules–1 s–1 for My-CIs (Deng et al., 2018). The concentration ranges of SO2 is about 1.7 × 1010 molecules cm3 in the boreal forest, 9 × 1010 molecules cm3 in a megacity and 6.6 × 109 molecules cm3 in rural Europe (Vereecken et al., 2012); thus the effective bimolecular rate of IM4 with respect to the reaction with SO2 is about 2.11–28.71 s–1. If SO2 is present in the atmosphere at a typical level of 5 × 1011 molecules cm3 (~20 ppbv) (Deng et al., 2018), the effective bimolecular rate of IM4 with respect to the reaction with SO2 is 159.5 s–1.

3.3 Fate of IM3

As shown in Fig. 4, the carbonyl compound IM3 can further react with O3, with ozone approaching the >C=C< bond forming a 5-member-ring IM8 compound via pre-reactant complexes (PRC3). This process contains a total excess energy of approximately 68.52 kcal mol–1, which is sufficient to cause rapid ring breakage. The primary product channels were identified as IM9 (CH3COCH2CH2CHOO·) + trans-glyoxal (OHCCHO) or levulinic aldehyde (CH3COCH2CH2CHO) + CIs (OHCCHOO·), with potential barriers of 16.63 and 24.76 kcal mol–1, respectively. The CIs OHCCHOO· and CH3COCH2CH2CHOO· can further react with H2O, SO2 and NO to form the stabilized products glyoxal and levulinic aldehyde, respectively.

Fig. 4. The fate of IM3 with O3 at the M06-2X/6-311++G(3df,3pd)//M06-2X/6-31+G(d,p) level of theory (kcal mol−1).Fig. 4. The fate of IM3 with O3 at the M06-2X/6-311++G(3df,3pd)//M06-2X/6-31+G(d,p) level of theory (kcal mol−1).


We applied quantum chemistry and kinetic calculations to identify the mechanism driving the ozonolysis of citral and gained the following insights:

  • POZs can be formed by the attachment of O3 to C=C, after which carbonyl molecules and CIs can be formed by the simultaneous cleavage of the C-C bond of the forming 5-member-ring and one of the O-O bonds.

  • CIs can isomerize at a rate of 59 × 10–3 s–1. Additionally, they can bimolecularly react with H2O and SO2 at rates of 193 s–1 and 159.5 s–1, respectively, and, to a far lesser degree, with NO (at a rate of 2.26 × 10–12 to 6.17 × 10–10 s–1). More importantly, CIs can oxidize SO2 into SO3, leading to the production of sulfuric acid.

The ozonolysis of citral potentially produces low-volatility species with increased water solubility, such as aldehydes [–C(=O)H], ketones [–C(=O)–], alcohols (–OH), and hydroperoxides (–OOH), which can form SOA through the nucleation, condensation, and/or partitioning of the condensed and gaseous phases.


This work is supported by National Natural Science Foundation of China (21607011, 21976109), Key Research and Development Project of Shandong Province (2019GSF109021, 2019GSF109037), and Natural Science Foundation of Shandong Province (ZR2018MB043).


  1. Alecu, I.M., Zheng, J., Zhao, Y., Truhlar, D.G. (2010). Computational thermochemistry: Scale factor databases and scale factors for vibrational frequencies obtained from electronic model chemistries. J. Chem. Theory Comput. 6, 2872–2887.

  2. Almatarneh, M.H., Elayan, I.A., Altarawneh, M., Hollett J.W. (2019). A computational study of the ozonolysis of sabinene. Theor. Chem. Acc. 138, 30.

  3. Anglada, J.M., Sole, A. (2016). Impact of the water dimer on the atmospheric reactivity of carbonyl oxides. Phys. Chem. Chem. Phys. 18, 17698–17712.

  4. Aplincourt, P., Ruiz-López, M.F. (2000). Theoretical investigation of reaction mechanisms for carboxylic acid formation in the atmosphere. J. Am. Chem. Soc. 122, 8990–8989.

  5. Atkinson, R. (1997). Gas-phase tropospheric chemistry of volatile organic compounds: 1. Alkanes and Alkenes. J. Phys. Chem. Ref. Data 26, 215–290.

  6. Atkinson, R., Arey, J. (2003). Gas-phase tropospheric chemistry of biogenic volatile organic compounds: A review. Atmos. Environ. 37, S197–S219.

  7. Berresheim, H., Adam, M., Monahan, C., O'Dowd, C.D., Plane, J.M.C., Bohn, B., Rohrer, F. (2014). Missing SO2 oxidant in the coastal atmosphere? – observations from high-resolution measurements of OH and atmospheric sulfur compounds. Atmos. Chem. Phys. 14, 12209–12223.

  8. Boy, M., Mogensen, D., Smolander, S., Zhou, L., Nieminen, T., Paasonen, P., Plass-Dulmer, C., Sipila, M., Petaja, T., Mauldin, L., Berresheim, H., Kulmala, M. (2013). Oxidation of SO2 by stabilized Criegee intermediate (sCI) radicals as a crucial source for atmospheric sulfuric acid concentrations. Atmos. Chem. Phys. 13, 3865–3879.

  9. Calogirou, A., Larsen, B.R., Kotzias, D. (1999). Gas-phase terpene oxidation products: A review. Atmos. Environ. 33, 1423–1439.

  10. Canneaux, S., Bohr, F., Henon, E. (2014). KiSThelP: A program to predict thermodynamic properties and rate constants from quantum chemistry results. J. Comput. Chem. 35, 82–93.

  11. Caravan, R.L., Vansco, M.F., Au, K., Khan, M.A.H., Li, Y.L., Winiberg, F.A.F., Zuraski, K., Lin, Y.H., Chao, W., Trongsiriwat, N., Walsh, P.J., Osborn, D.L., Percival, C.J., Lin, J.M., Shallcross, D.E., Sheps, L., Klippenstein, S.J., Taatjes, C.A., Lester, M.I. (2020). Direct kinetic measurements and theoretical predictions of an isoprene-derived Criegee intermediate. Proc. Natl. Acad. Sci. U.S.A. 117, 9733–9740.

  12. Chhantyal-Pun, R., Welz, O., Savee, J.D., Eskola, A.J., Taatjes, C.A. (2016). Direct measurements of unimolecular and bimolecular reaction kinetics of the Criegee intermediate (CH3)2COO. J. Phys. Chem. A 121, 4–15.

  13. Deng, P., Wang, L.Y., Wang, L.M. (2018). Mechanism of gas-phase ozonolysis of β-Myrcene in the atmosphere. J. Phys. Chem. A 122, 3013–3020.

  14. Friedman, B., Farmer, D.K. (2018). SOA and gas phase organic acid yields from the sequential photooxidation of seven monoterpenes. Atmos. Environ. 187, 335–345.

  15. Frisch, M.J., Trucks, G.W., Schlegel, H.B., Scuseria, G.E., Robb, M.A., Cheeseman, J.R., Scalmani, G., Barone, V., Mennucci, B., Petersson, G.A., Nakatsuji, H., Caricato, M., Li, X., Hratchian, H.P., Izmaylov, A.F., Bloino, J., Zheng, G., Sonnenberg, J.L., Hada, M., …, Fox, D.J. (2009). Gaussian 09. Revision B.01, Wallingford CT.

  16. Gil, A., van Baren, C.M., Di Leo Lira, P., Bandoni, A.L. (2007). Identification of the genotype from contents and composition of the essential oil of lemon verbena (Aloysia citriodora Palau). J. Agric. Food Chem. 55, 8664–8669.

  17. Goldstein, A.H., Galbally, I.E. (2007). Known and unexplored organic constituents in the earth’s atmosphere. Environ. Sci. Technol. 41, 1514–1521.

  18. Guenther, A., Hewitt, C.N., Erickson, D., Fall, R., Geron, C., Graedel, T., Harley, P., Klinger, L., Lerdau, M., Mckay, W. A., Pierce, T., Scholes, B., Steinbrecher, R., Tallamraju, R., Taylor, J., Zimmerman, P. (1995). A global-model of natural volatile organic compound emissions. J. Geophys. Res. 100, 8873–8892.

  19. Hallquist, M., Wenger, J., Baltensperger, U., Rudich, Y., Simpson, D., Claeys, M., Dommen, J., Donahue, N., George, C., Goldstein, A.H., Hamilton, J.F., Herrmann, H., Hoffmann, T., Iinuma, Y., Jang, M., Jenkin, M.E., Jimenez, J.L., Kiendler-Scharr, A., Maenhaut, W., …, Wildt, J. (2009). The formation, properties and impact of secondary organic aerosol: Current and emerging issues. Atmos. Chem. Phys. 9, 5155–5236.

  20. Huang, H.L., Chao, W., Lin, J.J.M. (2015). Kinetics of a Criegee intermediate that would survive high humidity and may oxidize atmospheric SO2. Proc. Natl. Acad. Sci. U.S.A. 112, 10857–10862.

  21. Jackson, S.R., Ham, J.E., Harrison, J.C., Wells, J.R. (2016). Identification and quantification of carbonyl-containing α-pinene ozonolysis products using O-tert-butylhydroxylamine hydrochloride. J. Atmos. Chem. 74, 325–338.

  22. Jackson, S.R., Harrison, J.C., Ham, J.E., Wells, J.R. (2017). A chamber study of alkyl nitrate production formed by terpene ozonolysis in the presence of NO and alkanes. Atmos. Environ. 171, 143–148.

  23. Jaoui, M., Edney, E.O., Kleindienst, T.E., Lewandowski, M., Offenberg, J.H., Surratt, J.D., Seinfeld, J.H. (2008). Formation of secondary organic aerosol from irradiated -pinene/toluene/NOx mixtures and the effect of isoprene and sulfur dioxide. J. Geophys. Res. 113, D09303. 10.1029/2007jd009426

  24. Jimenez, J.L., Canagaratna, M.R., Donahue, N.M., Prevot, A.S.H., Zhang, Q., Kroll, J.H., DeCarlo, P.F., Allan, J.D., Coe, H., Ng, N.L., Aiken, A.C., Docherty, K.S., Ulbrich, I.M., Grieshop, A.P., Robinson, A.L., Duplissy, J., Smith, J.D., Wilson, K.R., Lanz, V.A., …, Worsnop, D. (2009). Evolution of organic aerosols in the atmosphere. Science 326, 1525–1529.

  25. Kleindienst, T.E., Edney, E.O., Lewandowski, M., Offenberg, J.H., Jaoui, M. (2006). Secondary organic carbon and aerosol yields from the irradiations of isoprene and α-pinene in the presence of NOx and SO2. Environ. Sci. Technol. 40, 3807–3812.

  26. Kuwata, K.T., Guinn, E.J., Hermes, M.R., Fernandez, J.A., Mathison, J.M., Huang, K. (2015). A computational re-examination of the Criegee intermediate-sulfur dioxide reaction. J. Phys. Chem. A 119, 10316–10335.

  27. Lin, X.X., Liu, Y.R., Huang, T., Xu, K.M., Zhang, Y., Jiang, S., Gai, Y.B., Zhang, W.J., Huang, W. (2014). Theoretical studies of the hydration reactions of stabilized Criegee intermediates from the ozonolysis of β-pinene. RSC Adv. 4, 28490–28498.

  28. Long, B., Bao, J.L., Truhlar, D.G. (2019). Rapid unimolecular reaction of stabilized Criegee intermediates and implications for atmospheric chemistry. Nat. Commun. 10, 2003.

  29. Martínez, E., Cabañas, B., Aranda, A. Martín, P., Salgado, S. (1999). Absolute rate coefficients for the gas-phase reactions of NO3 radical with a series of monoterpenes at T = 298 to 433 K. J. Atmos. Chem. 33, 265–282.

  30. Mauldin, R.L., Berndt, T., Sipilä, M., Paasonen, P., Petäjä, T., Kim, S., Kurtén, T., Stratmann, F., Kerminen, V.M., Kulmala, M. (2012). A new atmospherically relevant oxidant of sulphur dioxide. Nature 488, 193–196.

  31. Messina, P., Lathière, J., Sindelarova, K., Vuichard, N., Granier, C., Ghattas, J., Cozic, A., Hauglustaine, D.A. (2016). Global biogenic volatile organic compound emissions in the ORCHIDEE and MEGAN models and sensitivity to key parameters. Atmos. Chem. Phys. 16, 14169–14202.

  32. Murray, L.T., Logan, J.A., Jacob, D.J. (2013). Interannual variability in tropical tropospheric ozone and OH: The role of lightning. J. Geophys. Res. 118, 11468–11480.

  33. Nagori, J., Janssen, R.H.H., Fry, J.L., Krol, M., Jimenez, J.L., Hu, W., Vilà-Guerau de Arellano, J. (2019). Biogenic emissions and land–atmosphere interactions as drivers of the daytime evolution of secondary organic aerosol in the southeastern US. Atmos. Chem. Phys. 19, 701–729.

  34. Neeb, P., Sauer, F., Horie, O., Moortgat, G.K. (1997). Formation of hydroxymethyl hydroperoxide and formic acid in alkene ozonolysis in the presence of water vapour. Atmos. Environ. 31, 1417–1423.

  35. Newsome, B., Evans, M. (2017). Impact of uncertainties in inorganic chemical rate constants on tropospheric composition and ozone radiative forcing. Atmos. Chem. Phys. 17, 14333–14352.

  36. Nguyen, T.B., Tyndall, G.S., Crounse, J.D., Teng, A.P., Bates, K.H., Schwantes, R.H., Coggon, M.M., Zhang, L., Feiner, P., Milller, D.O., Skog, K.M., Rivera-Rios, J.C., Dorris, M., Olson, K.F., Koss, A., Wild, R.J., Brown, S.S., Goldstein, A.H., de Gouw, J.A., …, Wennberg, P.O. (2016). Atmospheric fates of Criegee intermediates in the ozonolysis of isoprene. Phys. Chem. Chem. Phys. 18, 10241–10254.

  37. Oberdorster, G., Oberdorster, E., Oberdorster, J. (2005). Nanotoxicology: Anemerging discipline evolving from studies of ultrafine particles. Environ. Health Perspect. 113, 823–839.

  38. Oliveira, R.C.D.M., Bauerfeldt, G.F. (2012). Thermochemical analysis and kinetics aspects for a chemical model for camphene ozonolysis. J. Chem. Phys. 137, 134306.

  39. Orlando, J.J., Barbara Nozière, Tyndall, G.S., Orzechowska, G.E., Paulson, S.E., Rudich, Y. (2000). Product studies of the OH‐ and ozone‐initiated oxidation of some monoterpenes. J. Geophys. Res. 105, 11561–11572.

  40. Pope, C.A. III, Dockery, D.W. (2006). Health effects of fine particulate air pollution: Lines that connect. J. Air Waste Manage. Assoc. 56, 709–742.

  41. Presto, A.A., Huff Hartz, K. E., Donahue, N.M. (2005). Secondary organic aerosol production from terpene ozonolysis. 2. Effect of NOx concentration. Environ. Sci. Technol. 39, 7046–7054.

  42. Qi, B., Chao, Y.T. (2007). Theoretical study on the mechanism and kinetics of the reaction of Criegee radical CH2O2 with H2O. Acta Chim. Sinica 65, 2117–2123.

  43. Qin, M.M., Hu, Y.T., Wang, X.S., Vasilakos, P., Boyd, C.M., Xu, L., Song, Y., Ng, N.L., Nenes, A., Russell, A.G. (2018). Modeling biogenic secondary organic aerosol (BSOA) formation from monoterpene reactions with NO3: A case study of the SOAS campaign using CMAQ. Atmos. Environ. 184, 146–155.

  44. Rauber, C.S., Guterres, S.S., Schapoval, E.E.S. (2005). LC determination of citral in Cymbopogon citratus volatile oil. J. Pharm. Biomed. Anal. 37, 597–601.

  45. Ridley, D., Cain, M., Methven, J., Arnold, S. (2017). Sensitivity of tropospheric ozone to chemical kinetic uncertainties in air masses influenced by anthropogenic and biomass burning emissions. Geophys. Res. Lett. 44, 7472–7481.

  46. Saddiq, A.A., Khayyat, S.A. (2010). Chemical and antimicrobial studies of monoterpene: Citral. Pestic. Biochem. Phys. 98, 89–93.

  47. Sarwar, G., Fahey, K., Kwok, R., Gilliam, R.C., Roselle, S.J., Mathur, R., Xue, J., Yu, J.Z., Carter, W.P.L. (2013). Potential impacts of two SO2 oxidation pathways on regional sulfate concentrations: Aqueous-phase oxidation by NO2 and gas-phase oxidation by Stabilized Criegee Intermediates. Atmos. Environ. 68, 186–197.

  48. Sato, K., Jia, T., Tanabe, K., Morino, Y., Kajii, Y., Imamura, T. (2016). Terpenylic acid and nine-carbon multifunctional compounds formed during the aging of β-pinene ozonolysis secondary organic aerosol. Atmos. Environ. 130, 127–135.

  49. Sauer, F., Schäfer, C., Neeb, P., Horie, O., Moortgat, G.K. (1999). Formation of hydrogen peroxide in the ozonolysis of isoprene and simple alkenes under humid conditions. Atmos. Environ. 33, 229–241.

  50. Scorch, C., Wissenbach, D. K., Franck, U., Wendisch, M., Schlink, U. (2017). Degradation of indoor limonene by outdoor ozone: A cascade of secondary organic aerosols. Environ. Pollut. 226, 463–472.

  51. Shiroudi, A., Deleuze, M.S. (2014). Theoretical study of the oxidation mechanisms of naphthalene initiated by hydroxyl radicals: The H abstraction pathway. J. Phys. Chem. A 118, 4593–4610.

  52. Sipilä, M., Jokinen, T., Berndt, T., Richters, S., Makkonen, R., Donahue, N. M., Mauldin III, R. L, Kurten, T., Paasonen, P., Sarnela, N. (2014). Reactivity of stabilized Criegee intermediates (sCIs) from isoprene and monoterpene ozonolysis toward SOand organic acids. Atmos. Chem. Phys. 14, 12143–12153.

  53. Stangl, C.M., Krasnomowitz, J.M., Apsokardu, M.J., Tiszenkel, L., Ouyang, Q., Lee, S., Johnston, M.V. (2019). Sulfur dioxide modifies aerosol particle formation and growth by ozonolysis of monoterpenes and isoprene. J. Geophys. Res. 124, 4800–4811.

  54. Sun, J.F., Mei, Q., Wei, B., Huan, L., Xie, J., He, M.X. (2018). Mechanisms for ozone-initiated removal of biomass burning products from the atmosphere. Environ. Chem. 15, 83–91.

  55. Taatjes, C.A., Welz, O., Eskola, A.J., Savee, J.D., Scheer, A.M., Shallcross, D.E., Rotavera, B., Lee, E.P.F., Dyke, J.M., Mok, D.K.W., Osborn, D.L., Percival, C.J. (2013). Direct measurements of conformer-dependent reactivity of the Criegee intermediate CH3CHOO. Science 340, 177–180.

  56. Truhlar, D.G., Garrett, B.C., Klippenstein, S.J. (1996). Current status of transition-state theory. J. Phys. Chem. 100, 12771–12800.

  57. Vereecken, L., Harder, H., Novelli, A. (2012). The reaction of Criegee intermediates with NO, RO2, and SO2, and their fate in the atmosphere. Phys. Chem. Chem. Phys. 14, 14682–14695.

  58. Wang, L.Y., Wang, L.M. (2017). Mechanism of gas-phase ozonolysis of sabinene in the atmosphere. Phys. Chem. Chem. Phys. 19, 24209.

  59. Wang, X., Sun, J., Bao, L., Mei, Q., Wei, B., An, Z., Xie, J., He, M.X. (2019). Mechanisms and kinetic parameters for the gas-phase reactions of 3-methyl-3-buten-2-one and 3-methyl-3-penten-2-one with ozone. J. Phys. Chem. A 123, 2745–2755.

  60. Ye, J., Abbatt, J.P.D., Chan, A.W.H. (2018). Novel Pathway of SO2 oxidation in the atmosphere: Reactions with monoterpene ozonolysis intermediates and secondary organic aerosol. Atmos. Chem. Phys. 18, 5549–5565.

  61. Zhang, H., Yee, L.D., Lee, B.H., Curtis, M.P., Worton, D.R., Isaacman-VanWertz, G., Offenberg, J.H., Lewandowski, M., Kleindienst, T.E., Beaver, M.R., Holder, A.L., Lonneman, W.A., Docherty, K.S., Jaoui, M., Pye, H.O.T., Hu, W., Day, D.A., Campuzano-Jost, P., Jimenez, J.L., …, Goldstein, A.H. (2018). Monoterpenes are the largest source of summertime organic aerosol in the southeastern United States. Proc. Natl. Acad. Sci. U.S.A. 115, 2038–2043.

  62. Zheng, J.J., Zhao, Y., Truhlar, D.G. (2009). The DBH24/08 database and its use to assess electronic structure model chemistries for chemical reaction barrier heights. J. Chem. Theory Comput. 5, 808–821.

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