Yung-Chieh Tsao1, Pao-Erh Chang2, Shin-Yu Chen2,3, Yaw-Huei Hwang 1,4

  • 1 Institute of Occupational Medicine and Industrial Hygiene, National Taiwan University College of Public Health, Taipei, Taiwan
  • 2 Green Energy & Environment Research Laboratories, Industrial Technology Research Institute, Hsinchu, Taiwan
  • 3 Institute of Environmental Engineering, National Chiao Tung University, Hsinchu, Taiwan
  • 4 Department of Public Health, College of Public Health, National Taiwan University, Taipei 10617, Taiwan

Received: August 31, 2014
Revised: December 20, 2014
Accepted: March 15, 2015
Download Citation: ||  

  • Download: PDF

Cite this article:
Tsao, Y.C., Chang, P.E., Chen, S.Y. and Hwang, Y.H. (2015). Real-Time Fab-Wise Airborne Molecular Contaminant (AMC) Monitoring System Using Multiple Fourier Transform Infrared (FTIR) Spectrometers in a Semiconductor Plant. Aerosol Air Qual. Res. 15: 1640-1651.


  • The I/O ratio illustrated the dynamically changing concentrations.
  • The elevated outdoor chemicals were observed without previous indoor emission peaks.
  • The airborne chemicals accumulated in the outdoors possibly damage indoor air.



The objective of this study was to investigate the airborne pollutant emission sources and fluctuations around the indoor and outdoor environments of a semiconductor manufacturing plant using monitoring data that were collected over 4 consecutive days via three Fourier transform infrared (FTIR) spectrometers located near an outdoor make-up air unit and an indoor Fab and sub Fab. Based on a total of 1,032 five-minute-interval records, fourteen chemicals were detected. Six of these chemicals, namely, carbon tetrafluoride, nitrous oxide, carbon monoxide, silane, sulfur hexafluoride, and methane, had significant concentration correlations between the indoor and outdoor environments. With the exception of silane and sulfur hexafluoride, the percentage of indoor/outdoor concentration ratios that were greater than one ranged from 62.2% to 73.1%, indicating that the indoor chemical concentrations were typically higher than the outdoor concentrations.

Based on the regression models derived for the indoor and outdoor nitrous oxide concentrations, the nitrous oxide was believed to be originally emitted from the sub Fab vented to the outdoors and then partially returned to the Fab. It was estimated that for one ppb of nitrous oxide detected in the Fab, 2.58 ppb of nitrous oxide could be detected at the make-up air unit, which might result from the sub Fab emission being at a high level of 6.60 ppb. Furthermore, elevated outdoor concentrations of chemicals, such as carbon tetrafluoride, nitrous oxide and carbon monoxide, were observed without previous indoor emission peaks, indicating that these chemicals might accumulate in the outdoor surrounding area.

This study successfully illustrated the dynamically changing relationship between indoor and outdoor chemical concentrations in a semiconductor clean room. These results can be used to prevent subtle and potential adverse impacts of airborne molecular contaminant (AMC) in various manufacturing facilities of technological industries, including the semiconductor and optoelectronics industries.

Keywords: Fourier transform infrared (FTIR); Indoor/outdoor ratio (I/O ratio); Semiconductor; Airborne pollutants; Airborne molecular contaminant (AMC)

Share this article with your colleagues 


Subscribe to our Newsletter 

Aerosol and Air Quality Research has published over 2,000 peer-reviewed articles. Enter your email address to receive latest updates and research articles to your inbox every second week.

79st percentile
Powered by
   SCImago Journal & Country Rank

2023 Impact Factor: 2.5
5-Year Impact Factor: 2.8

Aerosol and Air Quality Research partners with Publons

CLOCKSS system has permission to ingest, preserve, and serve this Archival Unit
CLOCKSS system has permission to ingest, preserve, and serve this Archival Unit

Aerosol and Air Quality Research (AAQR) is an independently-run non-profit journal that promotes submissions of high-quality research and strives to be one of the leading aerosol and air quality open-access journals in the world. We use cookies on this website to personalize content to improve your user experience and analyze our traffic. By using this site you agree to its use of cookies.