Hui-Fen Chiu1, Chiung-Yu Peng2, Trong-Neng Wu3,4, Chun-Yuh Yang 2,4

  • 1 Department of Pharmacology, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan
  • 2 Department of Public Health, College of Health Sciences, Kaohsiung Medical University, Kaohsiung, Taiwan
  • 3 Department of Public Health, China Medical University, Taichung, Taiwan
  • 4 Division of Environmental Health and Occupational Medicine, National Health Research Institute, Miaoli, Taiwan

Received: January 16, 2013
Revised: April 24, 2013
Accepted: April 24, 2013
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Cite this article:
Chiu, H.F., Peng, C.Y., Wu, T.N. and Yang, C.Y. (2013). Short-Term Effects of Fine Particulate Air Pollution on Ischemic Heart Disease Hospitalizations in Taipei: A Case-Crossover Study. Aerosol Air Qual. Res. 13: 1563-1569.



This study was undertaken to determine whether there was a correlation between fine particles (PM2.5) levels and hospital admissions for ischemic heart disease (IHD) in Taipei, Taiwan. Hospital admissions for IHD and ambient air pollution data for Taipei were obtained for the period from 2006–2010. The relative risk of hospital admissions was estimated using a case-crossover approach, controlling for weather variables, day of the week, seasonality, and long-term time trends. For the single pollutant model (without adjustment for other pollutants), increased IHD admissions were significantly associated with PM2.5 on both warm (> 23°C) and cool days (< 23°C), with an interquartile range increase associated with a 12% (95% CI = 10%–14%) and 4% (95% CI = 2%–6%) increase in IHD admissions, respectively. In the two-pollutant models, PM2.5 remained significant after the inclusion of SO2 or O3 both on warm and cool days. This study provides evidence that higher levels of PM2.5 increase the risk of hospital admissions for IHD.

Keywords: Fine particulate; Air pollution; Hospital admissions; Ischemic heart disease; Case-crossover

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