Needle trap samplers (NTS), which are environmentally friendly solid phase microextraction sampling devices, were used to obtain air samples at a medical examination center in a teaching hospital to determine the concentration of xylene in the air. The standard active sampling method using, Method 1501, was simultaneously used to evaluate the exposures exposure of worker to xylene. The concentrations of xylene were much lower than the legal 100-ppm time weighted average (TWA) concentration. Another organic reagent that is used in the medical examination center, formaldehyde, did not exhibit co-adsorption along with the extraction of xylene by NTS. The use of a fume hood satisfactorily reduced VOC emissions in the work place. Additionally, a management strategy that involves chemical control banding was adopted to evaluate the emission control performance of xylene and formaldehyde in this work. The NTS is recommended for use as a routine micro-sampler to be worn by workers to protect their health.