The long-range transport of aerosols is a global issue, since it may affect significantly the air quality of regions without high concentrations of fine particulate matter (PM2.5). Two significant events of long-range transport of aerosols over Parana State, Brazil, which occurred on Aug. 16–18 and Sep. 10–14 of 2016 were studied in order to characterize the atmospheric synoptic conditions of these events and to estimate their contribution to the air quality conditions in the Northern region of the State. The South American Low Level Jet (SALLJ) was the key meteorological component used to define the origin of the air mass trajectories over region. In the first event, the SALLJ lost its configuration, bringing air masses from the west part of São Paulo state, while in the second event, the SALLJ organized over Southern Brazil, brought air masses from the North and Central parts of Brazil. The significant number of fires from biomass burning in Central Brazil associated with synoptic conditions contributed to increase the PM2.5 concentrations by around 70–87% in the region. The transport of aerosols was determinant to the exceedance of air quality standard of PM2.5 in the region. Therefore, to minimize this problem, it is imperative to control biomass burning in Brazil.